Abrar Hussain Qadri
PhD Scholar
Phone:
+91 70062 43987
Email:
Address:
F73B, Dr P Anil Kumar, Dept of Biochemistry,
School of Life Sciences, University of Hyderabad.
Abrar's Research Work
Abrar's work entails investigating the structural insights of the slit diaphragm protein CD2AP and its interacting partners PODOCIN and NEPHRIN and understanding how these proteins interact to form the macromolecular complexes called the Slit diaphragm (SD). The crucial role of SD is in the filtration of blood and the formation of urine. In nephrotic syndrome, mutations in these SD proteins disrupt the macromolecular complex, leading to proteinuria nephrotic syndrome and eventually end-stage renal failure. Due to challenges in obtaining slit-diaphragm protein solutions, their structural information has been scant for decades.
Work Experience
July 2019 - (Present)
March 2016 - June 2018
March 2012 - May 2015
PhD Scholar,
University of Hyderabad,
Hyderabad, Telangana - 500046.
M.Sc in Biochemistry,
University of Kashmir,
Srinagar, Jammu and Kashmir - 190006.
B.Sc in Biochemistry,
Government Degree College Anantnag,
Anantnag, Jammu and Kashmir - 192101.
Publication:
1. Mulukala SKN, Kambhampati V, Qadri AH, Pasupulati AK. Evolutionary conservation of intrinsically unstructured regions in slit-diaphragm proteins. PLoS One. 2021;16(7):e0254917. doi: 10.1371/journal.pone.0254917. eCollection 2021. PubMed PMID: 34288970; PubMed Central PMCID: PMC8294545.
2. Abrar H Qadri, Jyotsana Prajapati, Iqball Faheem, Utsa Bhattacharjee, Hari Krishnan Padmanaban, Sandeep KN Mulukaka, Anil K Pasupulati. Biophysical characterization and insights into the oligomeric nature of CD2-associated protein. Int. J Biochem Mol Biol 2024;15(2). doi: 10.62347/UVSH8436
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